Sorrow

sor·row Pronunciation (sr, sôr)
n.
1. Mental suffering or pain caused by injury, loss, or despair. Synonyms: regret.
2. A source or cause of sorrow; a misfortune.
3. Expression of sorrow; grieving.
intr.v. sor·rowed, sor·row·ing, sor·rows
To feel or express sorrow. Synonyms: grieve.
[Middle English sorwe, from Old English sorg.]

sorrow - an emotion of great sadness associated with loss or bereavement; "he tried to express his sorrow at her loss"